Phospholipase A2/重组蜜蜂毒液磷脂酶A2 P00630
- 产地：福建 厦门市
- 供应商：厦门慧嘉生物科技有限公司
- 供应商报价： 电议
- 标签：Phospholipase A2/重组蜜蜂毒液磷脂酶A2 P00630,Phospholipase A2/重组蜜蜂毒液磷脂酶A2 P00630价格,Phospholipase A2/重组蜜蜂毒液磷脂酶A2 P00630厂家
产品库
| Synonyms | Phospholipase A2, Phosphatidylcholine 2-acylhydrolase, Allergen Api m I, Api m 1. |
| Introduction | Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14–16-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies. |
| De | The E.Coli derived recombinant protein contains phospholipase P00630 bee venom protein epitopes, 26-162 amino acids. |
| Method | Purified by proprietary chromatographic technique. |
| Purity | Protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC. |
| Formulation | 10mM Tris-HCl, pH 6.5, 0.1M Sodium Phosphate and 8M urea. |
| Storage | Protein is shipped at ambient temperature. Upon arrival, Store at -20°C. |
| Stability | Five years frozen. One month in solution at room temperature. |
| Applications | : Use as an antigen in ELISA and Western Blots. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
