Nalidixic acid/萘啶酸
产品编号：N011
产品规格：25g/100g
| CAS Number | 389-08-2 |
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| Molecular Formula | C12H12N2O3 |
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| Molecular Weight | 232.24 g/mol |
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| Form | Powder |
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| Appearance | White or off-white crystalline powder |
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| Purity Level | ≥99.0% |
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| Solubility | Methylene chloride: Soluble
Water: 0.1 mg/mL |
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| Source | Synthetic |
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| Water Content (Karl Fisher) | Loss on drying: <0.5% |
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| Boiling Point | 413.1 °C |
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| Melting Point | 225-231 °C |
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| Flash Point | 203.6 °C |
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| Storage Conditions | 2-8 °C |
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Description
Nalidixic acid is a naphthyridone antibiotic similar in structure and mechanism to quinolones.
TOKU-E offers two forms of nalidixic acid: nalidixic acid (N011) and nalidixic acid sodium salt (N001). Nalidixic acid is sparingly soluble in aqueous solution at 0.1 mg/mL. Nalidixic acid sodium salt is freely soluble in aqueous solution at 50 mg/mL.
Mechanism
Nalidixic acid indirectly inhibits proteins synthesis by binding DNA and interfering with enzymes involved in DNA replication and transcription.
Spectrum
Nalidixic acid is a broad spectrum antibiotic commonly used against bacteria responsible for urinary tract infections.
Microbiology Applications
