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C041 D-Cycloserine/D- 环丝氨酸

产品信息
D-Cycloserine/D- 环丝氨酸
产品编号:C041 
产品规格:1g/5g
CAS Number68-41-7
Molecular FormulaC3H6N2O2
Molecular Weight102.09 g/mol
FormPowder
AppearanceWhite to pale white crystalline powder
Purity Level98.0-102.0%
SolubilityWater: Freely soluble

Note: Stable in solutions buffered to pH 10 with sodium carbonate.
SourceSynthetic
pH5.5-6.5
Melting Point147 °C
Optical Rotation+108o to +114o
Storage Conditions-20 °C
Description
D-cycloserine is an amino acid analog antibiotic. D-cycloserine acts as a competitive inhibitor of D-alanine, an essential amino acid during peptidoglycan synthesis. D-cycloserine is soluble in aqueous solution.
Mechanism
D-Cycloserine inhibits cell wall biosynthesis (D-Ala peptide bond formation). The terminal two amino acid residues of the murein precursor lipid II consist of D-alanine, which is produced by the enzyme alanine racemase; the two residues are joined by D-alanine ligase. Both enzymes are competitively inhibited by cycloserine.
Spectrum
D-cycloserine broad spectrum antibiotic but is largely used against bacteria which cause tuberculosis namelyMycobacterium tuberculosis.
Microbiology Applications
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