C023 Cefuroxime sodium/头孢呋辛钠
- 型号：C023
- 产地：福建 厦门市
- 供应商：厦门慧嘉生物科技有限公司
- 供应商报价： 电议
- 标签：Cefuroxime sodium/头孢呋辛钠,Cefuroxime sodium/头孢呋辛钠价格,Cefuroxime sodium/头孢呋辛钠厂家
产品信息
Cefuroxime sodium/头孢呋辛钠
产品编号：C023
产品规格：1g/5g
| CAS Number | 56238-63-2 |
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| Molecular Formula | C16H15N4NaO8S |
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| Molecular Weight | 446.37 g/mol |
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| Form | Powder |
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| Appearance | White to yellowish crystalline powder |
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| Purity Level | ≥95.0% |
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| Solubility | Water: Freely soluble |
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| Source | Synthetic |
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| Water Content (Karl Fisher) | <3.5% |
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| pH | 6.0-8.5 |
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| Melting Point | 240-245 °C |
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| Optical Rotation |
+55° to +65o |
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| Storage Conditions | 2-8 °C |
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Description
Cefuroxime sodium is a second generation cephalosporin antibiotic and is freely soluble in aqueous solution (0.145 mg/mL).
Mechanism
like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases. like many second generation cephalosporins, cefuroxime is relatively stable in the presence of β-lactamases.
Spectrum
Cefuroxime sodium is a broad spectrum antibiotic targeting a wide variety of gram negative and gram positive bacteria.
Microbiology Applications
Cefuroxime sodium is commonly used in clinical in vitro microbiological
