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Asc-392 Cyclopamine/环巴胺

产品信息
Cyclopamine/环巴胺
产品编号:Asc-392 
产品规格:1mg/5mg
Cyclopamine      Hh signaling inhibitor
Purity: >97%

Biological Description

Cell permeable inhibitor of hedgehog (Hh) signaling, via direct inhibition of Smo (Smoothened), the accessory protein to the putative Hh receptor. Anti-cancer and teratogenic activity in vivo.


Useful References

Chen et al (2002) Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev. 16:2743-8.link

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