免疫原： Recombinant human protein was used as the immunogen for the Tyrosinase antibody.
规格： 100 ug
产品类型： Primary antibody 纯化方法： Purified 通用信息： 1 mg/ml in 1X PBS; BSA free, sodium azide free 产品描述： Recognizes a cluster of proteins between 70-80kDa, identified as tyrosinase. Occasionally a minor band at 55kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas. 联系方式：
![Mouse anti-Human <em>Tyrosinase</em> <em>Antibody</em> (<em>TYR</em>) [Sodium Azide Free]](https://item.yiqi.com/pic/CovPic/4/3368549659970264002-14.jpg)
