11-deoxy-16,16-dimethyl Prostaglandin E2,7-[(1R,2R)-2-[(3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid,53658-98-3

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试剂描述：

产品名称：11-deoxy-16,16-dimethyl Prostaglandin E2

产品别名：11-deoxy-16,16-dimethyl PGE2

CAS号：53658-98-3

英文别名：11-deoxy-16,16-dimethyl PGE2

分子量：364.5

分子式：C₂₂H₃₆O₄

纯度：>98%

外观：见爱必信官网

保存方法：Store at -20° C

描述：11-deoxy-16,16-dimethyl Prostaglandin E2 is a stable synthetic analog of PGE2 , that has been shown to act as a selective agonist for both EP2 and EP3 receptors, unlike PGE2 which agonizes a variety of prostanoid receptors. This compound has shown effective inhibition of gastric acid secretion and ulcer formation in the rat, with ED₅₀ values of 1 mg/kg and 0.021 mg/kg, respectively, and is 900 times more potent than PGF2α in the contraction of human respiratory tract smooth muscle in vitro.

应用：An analog of PGE2 shown to act as a selective agonist for EP2 & EP3 receptors

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