产品库

CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody - Without BSA

产品信息
  • Prouduct:We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody - Without BSA.Functiong:Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.Summary:This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified intoĀthree main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain.ĀCD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi’s sarcoma, but with a lower specificity.
  • 信息声明:本产品供应信息由仪器网为您整合,供应商为(安诺伦(北京)生物科技有限公司),内容包括 ( CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody - Without BSA)的品牌、型号、技术参数、详细介绍等;如果您想了解更多关于 ( CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody - Without BSA)的信息,请直接联系供应商,给供应商留言!
    供应商产品推荐
      您可能感兴趣的产品