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LARGE antibody| LARGE抗体

产品信息
  • LARGE抗体| LARGE antibody

    货号  PAab04697

    蛋白别名  KIAA0609 antibody, LARGE1

    蛋白介绍

    Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:22223806). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide (PubMed:25279699).


    产品描述

    anti-LARGE antibody is a Rabbit Polyclonal antibody againstLARGE..

    建议稀释比例


    IHC


    Western blot

    (本抗体仅供体外科研用途,不可用于临床诊断!)

     

    武汉维克赛思科技有限公司

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