HNRNPK antibody| HNRNPK抗体

HNRNPK抗体| HNRNPK antibody

货号  PAab03955

蛋白别名  HNRPK

蛋白介绍

One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single- stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.

产品描述

anti-HNRNPK antibody is a Rabbit Polyclonal antibody againstHNRNPK..

建议稀释比例

IHC

Immunohistochemistry of paraffin-embedded human breast cancer using PAab03955(HNRNPK antibody) at dilution of 1:50

Western blot

HeLa cells were subjected to SDS PAGE followed by western blot with PAab03955(HNRNPK antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!)

 

武汉维克赛思科技有限公司

地址：武汉东湖新技术开发区东信路光谷创业街10栋

联系人：童经理

联系电话：13118103892
Email: info@vecscience.com

微信：13118103892

QQ: 3128136151