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GITR pure/CD357 (GITR) antibodies – functional grade, mouse

产品信息



  • 品Pai:miltenyi，产品名称：Anti-GITR pure, mouse - Funct Grade
    CD357 (GITR) antibodies – functional grade, mouse - Miltenyi Biotec
    货号：130-092-655
    Clone DTA-1 specifically recognizes mouse GITR (Glucocorticoid-induced TNF-receptor), a member of the TNF receptor superfamily1 also known as TNFRSF182. It is expressed at low levels on resting T lymphocytes and at high levels on CD4+CD25+ regulatory T cells (Tregs). Activation of T cells upregulates GITR expression. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation. GITR plays an important role in the function of CD4+CD25+ Tregs.3

    Alternative namesTNFRSF18, AITR
    Clone and isotype
    CloneIsotype
    DTA-1rat IgG2bκ

    温馨提示：不可用于临床ZL。
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