Cy5 carboxylic acid (non-sulfonated)
- 品牌：APExBIO
- 型号：5mg///25mg
- 供应商：上海伟寰生物科技有限公司
- 供应商报价：￥2100 - 4100
- 标签：Cy5 carboxylic acid (non-sulfonated)、Cy5 carboxylic acid (non-sulfonated)价格、Cy5 carboxylic acid (non-sulfonated)厂家、、APExBIO、上海伟寰生物科技有限公司
产品库
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| 分子式 | C32H39ClN2O2 | 分子量 | 519.12 |
| 溶解性 | >51.9mg/mL in DMSO | 储存条件 | 24 months after receival at -20° in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
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Cy5 carboxylic acid is a non-activated carboxylic acid with low aqueous solubility. For coupling with amines, or protein labeling, Cy5 NHS ester and water-soluble sulfo-Cy5 NHS ester is preferred. This labeling dye has limited water solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.
In the cells, The Cy5 carboxylic acid label on the dye can track the efficiency of the protein expression [1].
Reference:
[1] Deyle, K. M.; Farrow, B.; Hee, Y.Q.; Work, J.; Wong, M.; Lai, B.; Umeda, A.; Millward, S.W.; Nag, A.; Das, S.; Heath, J.R. A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1. Nature Chemistry,2015, 7, 455–462.
