商品分类:多克隆抗体
产品概述:MIST is a member of the SLP76 family of adaptors (seeLCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in theregulation of immunoreceptor signaling, including PLC-gamma (PLCG1;MIM 172420)-mediated B cell antigen receptor (BCR) signaling andFC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast celldegranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al.,2000, 2001 [PubMed 10744659] [PubMed 11463797]).
靶点/蛋白:This MIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human MIST.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Cronin, S., et al. Eur. J. Hum. Genet. 17(2):213-218(2009)Goitsuka, R., et al. J. Biol. Chem. 276(38):36043-36050(2001)Goitsuka, R., et al. Int. Immunol. 12(4):573-580(2000)Cao, M.Y., et al. J. Exp. Med. 190(10):1527-1534(1999)
特异性:Human
别名:Cytokine-dependent hematopoietic cell linker, Mast cell immunoreceptor signal transducer, CLNK, MIST
应用:WB~~1:1000
简单描述:Rabbit Polyclonal MIST Antibody (Center). Validated for use in WB, E.
详情:FunctionPlays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT (By similarity).
生物商城:http://www.annoron.com
办公电话:010-56256916
官方售后:400-965-8633
企业 QQ:3212874516、3198592576
地 址:北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示:不可用于临床ZL。