商品分类：单克隆抗体
产品概述：Secreted protein acidic and rich incysteine/osteonectin/BM40, or SPARC, is a matrix-associated proteinthat elicits changes in cell shape, inhibits cell-cycleprogression, and influences the synthesis of extracellular matrix(ECM) (Bradshaw et al., 2003 [PubMed 12721366]).
靶点/蛋白：This SPARC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the C-terminal region of human SPARC.
来源：Mouse
存储溶液：Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
参考文献：Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Howard, C., et al. Histol. Histopathol. 25(9):1163-1169(2010)Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :Liang, J.F., et al. J. Exp. Clin. Cancer Res. 29, 71 (2010) :
特异性：Human
别名：SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine, SPARC, ON
应用：WB~~1:100~800
简单描述：Mouse Monoclonal SPARC Antibody(C-term) Antibody(Ascites). Validated for use in WB, E. Clone: 664CT7.3.1.
详情：FunctionAppears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.Cellular_LocationSecreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
