Norepinephrine Transporter Antibody | LM19145 | Leading Biology

商品分类：单克隆抗体

产品概述：Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression (Klimek et al., 1997). Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD (Kim et al., 2006).

靶点/蛋白：Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.

来源：Mouse

存储溶液：Protein G purified culture supernatant.

参考文献：Klimek V, Stockmeier C, Overholser J, Meltzer HY, Kalka S, Dilley G, Ordway GA (1997)Reduced levels of norepinephrine transporters in the locus coeruleus in major depression. J.Neurosci. 17(21):8451-8458Kim CH, Hahn MK, Joung Y, Anderson SL, Steele AH, Mazei-Robinson MS, Gizer I, TeicherMH, Cohen BM, Robertson D, Waldman ID, Blakely RD, Kim KS (2006) A Polymorphism in thenorepinephrine transporter gene alters promoter activity and is associated with attention-deficithyperactivity disorder. Proc Nat’l Acad Sci USA 103(50):19164-9.

特异性：Mouse, Rat

别名：Sodium-dependent noradrenaline transporter, Norepinephrine transporter, NET, Solute carrier family 6 member 2, Slc6a2

应用：WB~~ 1:2000

简单描述：Mouse monoclonal Norepinephrine Transporter Antibody. Validated for use in WB. Clone: NET-05.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层