Human PECAM-1/CD31/重组人PECAM-1/CD31

Human PECAM-1/CD31/重组人PECAM-1/CD31
产品编号：100-386
产品规格：50μg
Description: PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein containing a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions.
Source: Hek 293
Molecular Weight: 80-95 kDa
Purity: >97% by SDS-PAGE and HPLC analysis
Endotoxin level/内毒素水平: < 0.1 ng per μg of PECAM-1
Formulation: lyophilized
Biological Activity: Testing in progress!
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted human PECAM-1 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Usage: Human PECAM-1 is offered for research use. Not for drug use. Not for human use.