商品分类:多克隆抗体
产品概述:Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
靶点/蛋白:Human SGK2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SGK3 (67%).
来源:Rabbit
参考文献:Kobayashi T.,et al.Biochem. J. 344:189-197(1999).Li H.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.Deloukas P.,et al.Nature 414:865-871(2001).Henke G.,et al.Kidney Blood Press. Res. 25:370-374(2002).
特异性:Human, Bovine
别名:Serine/threonine-protein kinase Sgk2, 2.7.11.1, Serum/glucocorticoid-regulated kinase 2, SGK2
应用:IHC-P (10 μg/ml)
简单描述:Rabbit Polyclonal SGK2 Antibody (Kinase Domain). Validated for use in IHC-P, E.
详情:FunctionSerine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.Cellular_LocationCytoplasm. NucleusTissue_LocationHighly expressed in liver, kidney and pancreas, and at lower levels in brain
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