重组人MutS同系物6/MSH6 Human
- 产地：福建 厦门市
- 供应商：厦门慧嘉生物科技有限公司
- 供应商报价： 电议
- 标签：重组人MutS同系物6/MSH6 Human,重组人MutS同系物6/MSH6 Human价格,重组人MutS同系物6/MSH6 Human厂家
产品库
| Catalogue Number | PRO-745 |
| Synonyms | MSH6, GTBP, HNPCC5, HSAP, DNA mismatch repair protein Msh6, MutS-alpha 160 kDa subunit, G/T mismatch-binding protein, hMSH6, p160, GTMBP. |
| Introduction | MSH6 deficiency result in hereditary non-polyposis colorectal cancer (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease MSH6 is involved in repairing DNA. MSH6 protein repairs mistakes that occure during DNA replication in preparation for cell division. The MSH6 protein bonds with MSH2 protein and form an active protein complex which recognizes specific parts on the DNA where mistakes have been made during DNA replication. MLH1-PMS2 protein complex, afterwards takes over with the repair. MSH6 gene is part of the set of the mismatch repair (MMR) genes. |
| De | MSH6 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 51 amino acids (350-400 a.a.) having a total Mw of 33 kDa. Human MSH6 is fused to a GST tag and purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | MSH6 is supplied in 50mM Tris-HCl, pH-7.5, 10mM L-glutathione (reduced). |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
